Paul Knoepfler
‘Wild West of CRISPR’? Ukraine clinic promises to gene edit graying hair, skin quality and breast size
If I had to pick one country that might be the epitome of the ‘Wild West’ of reproductive and genetic ...
Viewpoint: Why we need a 3-year moratorium on gene-edited babies
Chinese researcher He [Jiankui] dropped the bomb with his claim that he produced twin CRISPR’d babies. He cited a 2017 National Academies ...
Human chimera research key to understanding unknown aspects of human development
How is it possible that we understand exquisitely well how worms, fruit flies, and rodents develop, but our own species’ ...
Anti-CRISPR political groups emerging in Europe
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Campaigns are underway in ...
Proposed US legislation could threaten stem cell therapy safety
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Senators Mark Kirk, Joe ...
Designer baby dilemma: Germline DNA modifications not reversible
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. There’s a questionable notion ...
‘GMO Sapiens’: We need to put brakes on human genome editing
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. I've written a new ...
Google experimenting with CRISPR, gene drive technology
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Google is reportedly getting ...
‘GMO sapiens’ book explores future of human genetic modification
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. I’ve written a new ...
Some stem cell clinics offer costly, unproven procedures, in US and abroad
Stem cell treatments of various kinds are now widely available in America at more than 100 stem cell clinics offering ...
Genetically engineered animals with CRISPR-Cas9 edited genes are being developed
As CRISPR-Cas9 gene editing technology has advanced in the last few years, the number of genetically modified animals made with ...
Is ‘genetically modified human’ an accurate term if germline editing ever comes into use?
During the still ongoing discussions of genetic modification in the human germ line and potentially in actual human beings in ...
Does size matter enough to inject stem cells directly into your penis?
Does size matter? Can a man get bigger and could he do it via stem cells? An increasing number of ...
Where does the world stand on human germline gene editing?
In a still ongoing on-line poll, readers of the Knoepfler Lab Stem Cell blog show a pattern of consistently favoring a moratorium ...
New stem cell clinic feigns government approval with provocative name
Some American stem cell clinics that operate without FDA approval can give the appearance of being in the mainstream of ...
Same sex couples may eventually have biological children
Since Shinya Yamanaka reprogrammed first mouse and then human ordinary cells into powerful pluripotent stem cells, termed induced pluripotent stem ...
Finding a happy medium in regulation of stem cell research
When I started blogging in 2010 the stem cell arena was a very different place. Back then the hot topic ...
Does FDA underregulate stem cell treatments?
NBC News did a big on-line story followed by a NBC Nightly News Segment on dubious stem cell therapies on Friday. Normally a ...
Interview with FDA on dubious direct-to-consumer stem cell practices
I requested an interview with the FDA to cover the key pressing issues in this direct-to-consumer stem cell interventions. I ...
Pominent US biologist lectures UK Parliament: ‘Three-parent’ IVF too uncertain to be safe
This open letter was written by Paul Knoepfler, associate professor in the Department of Cell Biology and Human Anatomy, the Genome ...
Epigenetic cellular controls key for sperm and cancers
Sometimes in science there are unexpected threads tying seemingly very different things together. Unraveling the knots in these threads can ...
Retracted STAP stem cell papers first rejected at another journal; reviewers’ comments now public
Before the two STAP cell papers were published in Nature in January of 2014, much of the same data was ...
Duke stem cell trial for autism dangerously speculative?
Can stem cells be used to treat autism? At this point the jury remains out on that question, but a ...
Brain cancer may have rogue stem cell origin, option for treatment
Glioblastoma and other related malignant glioma tumors including diffuse intrinsic pontine glioma (DIPG) are some of the most devastating of ...
‘Right to try’ law, for profit stem cells make Colorado wild West of non-FDA clinical trials
Colorado passed a new law supported by the ultra-conservative Goldwater Institute, the so-called Right To Try Law. This law allows ...
Further advancement for MS stem cell treatments
There is more good news from leading stem cell biotech Advanced Cell Technology (ACT) on preclinical rodent studies using stem ...
Stem cell scientist outlines his top five challeges for embryonic stem cell nuclear transfer
It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human ...