Genetic manipulation extends mouse lifespan by 20%

LongevityMice WSJ
The mouse with the manipulated gene, which resulted in the longevity boost (right) and an unmodified mouse (left). Image via Wall Street Journal. Credit: NIH/NLBI

By reducing the activity of one type of gene, scientists said they increased the average life span of mice by about 20%, and preserved memory, cognition and other traits into old age.

Though mouse studies don’t always translate to humans, Dr. Finkel and other researchers said the results raise the possibility that targeting the gene with drugs that inhibit its activity might one day be at least part of a strategy for prolonging longevity in people.But researchers don’t know if whether inhibiting the action of the gene would have similar life-extending effects in humans, and if it did whether the benefit would come without unwanted problems.

Read the full, original story here: Genetic Manipulation Extends Life of Mice 20%

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