Restless genes: how the human compulsion to explore is a defining part of human success

| December 18, 2012 |

What drove us out from Africa and on to the moon and beyond?

If an urge to explore rises in us innately, perhaps its foundation lies within our genome. In fact there is a mutation that pops up frequently in such discussions: a variant of a gene called DRD4, which helps control dopamine, a chemical brain messenger important in learning and reward. Researchers have repeatedly tied the variant, known as DRD4-7R and carried by roughly 20 percent of all humans, to curiosity and restlessness. Dozens of human studies have found that 7R makes people more likely to take risks; explore new places, ideas, foods, relationships, drugs, or sexual opportunities; and generally embrace movement, change, and adventure. Studies in animals simulating 7R’s actions suggest it increases their taste for both movement and novelty. (Not incidentally, it is also closely associated with ADHD.)

View the original article here: Restless Genes